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Actavis Promethazine Codeine cough syrup (Each 5 mL contains) Promethazine hydrochloride: 6.25mg codeine phosphate: 10mg. Alcohol: 7%. Indication: Cough Suppressant Dosage Form: Syrup Validity: 2yrs Strength: 200mg Drug :1622-62-44 available in :16oz pint, 32oz pint, 8oz pint. Uses This combination medication is used to treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (e.g., sinusitis, bronchitis). Promethazine is an antihistamine that relieves watery eyes, itchy eyes/nose/throat, runny nose, and sneezing. Codeine is an opioid cough suppressant (antitussive) that affects a certain part of the brain, reducing the urge to cough. Opioid cough suppressants should not be used in children younger than 18 years. Children are at higher risk for serious (even fatal) side effects, especially breathing problems. Talk with the doctor about the risks and benefits of this medication. Cough-and-cold products do not cure colds. Cough due to a common cold often does not need to be treated with medicine. Ask your doctor or pharmacist about other ways to relieve cough and cold symptoms, such as drinking enough fluids, using a humidifier, or saline nose drops/spray.